Skip to main content

Best Happy Hour Mexican Restaurants in Midtown East (10022)

4 hand-picked restaurants, critic-reviewed and ranked

Last Updated: January 2026

Our Top Pick
Ánimo!
Serious, from-scratch Mexican breakfast burritos in a design-forward café setting.

Notable Picks

8.4
$ Midtown East
Ánimo! is a compact, design-forward Mexican spot where chef Jonathan Barragán leans into scratch-made chilaquiles, handmade tortillas, and deeply flavored moles. A focused 5–7pm happy hour pushes well-built agave cocktails and a few hearty antojitos, making it one of the strongest after-work Mexican plays in Midtown East.
Must-Try Dishes: Burrito Sonora (egg, cheese, chorizo, lettuce, tomato), Barbacoa Breakfast Burrito, Carne a la Tampiqueña Burrito-style plate
What makes it special: Serious, from-scratch Mexican breakfast burritos in a design-forward café setting.
$$$ Turtle Bay
This Midtown East outpost of Rosa Mexicano pairs a colorful, high-energy room with tableside guacamole, big-format margaritas, and familiar combo plates. It’s more about festive group outings than boundary-pushing cuisine, but remains a reliable option for crowd-pleasing Mexican in the neighborhood.
Must-Try Dishes: Guacamole en Molcajete, Enchiladas Roasted Chicken Suizas, Birria Quesatacos
What makes it special: Long-running Rosa Mexicano location with signature tableside guacamole and festive energy.
$$$ Midtown East
The long-running Second Avenue Rosa Mexicano leans festive, with colorful decor, big-format margaritas, and familiar Mexican standards. It’s less about culinary fireworks and more about dependable guacamole, tacos, and enchiladas for groups who want a lively, affordable-ish Midtown celebration spot.
Must-Try Dishes: Tableside Guacamole, Birria Quesatacos, Enchiladas Suizas
What makes it special: A festive, long-standing Mexican spot near the UN for groups and celebrations.

Worthy Picks

$ Midtown East
Tacovision is a narrow, two-level taco bar built for after-work drinks, with mix-and-match tacos, a Mexican pizza, and margarita flights. A dependable 5–7pm happy hour keeps cocktails and tacos relatively accessible for Midtown, making it a practical spot to start a night out near the office.
Must-Try Dishes: Al Pastor Tacos, Fish Tacos, Mexican Pizza
What makes it special: Focused taco-and-margarita bar built around flights, specials, and after-work energy.