Skip to main content

Best Mexican Restaurants in Midtown East (10022)

3 hand-picked restaurants, critic-reviewed and ranked

Last Updated: January 2026

Our Top Pick
Empellón
Ambitious, chef-driven tacos and tasting menus in a polished Midtown setting.

Notable Picks

$$$$ Midtown East
Alex Stupak’s Midtown flagship leans into inventive, Mexican-influenced plates, from pastrami tacos to corn ice cream tacos, in a sleek, high-energy room. It’s the most polished option in the neighborhood for serious agave, chef-y tacos, and expense-account fajitas.
Must-Try Dishes: Pastrami Tacos, Rib Steak Fajitas, Corn Ice Cream Tacos
What makes it special: Ambitious, chef-driven tacos and tasting menus in a polished Midtown setting.
$$$ Turtle Bay
This Midtown East outpost of Rosa Mexicano pairs a colorful, high-energy room with tableside guacamole, big-format margaritas, and familiar combo plates. It’s more about festive group outings than boundary-pushing cuisine, but remains a reliable option for crowd-pleasing Mexican in the neighborhood.
Must-Try Dishes: Guacamole en Molcajete, Enchiladas Roasted Chicken Suizas, Birria Quesatacos
What makes it special: Long-running Rosa Mexicano location with signature tableside guacamole and festive energy.

Worthy Picks

$ Midtown East
Dos Toros’ 54th & Lex location delivers Mission-style burritos, bowls, and quesadillas with quick counter service and reliable customization. It’s a practical, affordable option for a fast Mexican lunch near the office rather than a sit-down destination.
Must-Try Dishes: Mission-Style Burrito, Burrito Bowl, DT Quesadilla
What makes it special: Fast, customizable Cal-Mex burritos and bowls that outpace typical corporate chains.