Best Mexican Restaurants in River North (60654)
11 hand-picked restaurants, critic-reviewed and ranked
Last Updated: January 2026
Our Top Pick
Topolobampo
Michelin-starred tasting menus that showcase Mexico’s sauces, regions, and seasons.
Essential Picks
#1
Topolobampo
9.1
Rick Bayless’s fine-dining flagship runs refined, mole-driven tasting menus that lean into regional Mexican storytelling. Locals and destination diners alike use it for special-occasion dinners where complex sauces, agave pairings, and polished service justify the splurge.
Must-Try Dishes:
Feast of the Seven Moles tasting menu, Callo de Hacha scallop course, Mole negro with wagyu
What makes it special: Michelin-starred tasting menus that showcase Mexico’s sauces, regions, and seasons.
Notable Picks
8.8
Vibes:
Group Dining Gatherings
Comfort Food Classics
Trendy Table Hotspots
Family Friendly Favorites
Since the late 1980s, Frontera Grill has been Chicago’s benchmark for regionally inspired Mexican cooking, mixing seasonal ceviches, moles, and wood-grilled meats in a bustling room. It’s the move when you want serious flavor and agave cocktails without full tasting-menu formality.
Must-Try Dishes:
Carne Asada, Ceviche Trio, Queso Fundido
What makes it special: Long-running flagship for seasonal, regional Mexican with serious agave cocktails.
#3
Tzuco
8.7
Vibes:
Date Night Magic
Trendy Table Hotspots
Instagram Worthy Wonders
Birthday & Celebration Central
Chef Carlos Gaytán’s Tzuco fuses French technique with Mexican flavors in a plant-filled, design-forward dining room. Signature dishes like cochinita pibil and aguachiles make it a go-to for date nights and upscale group dinners that still feel lively rather than stiff.
Must-Try Dishes:
Cochinita Pibil pork shank, Esquites con carne, Hamachi jaws
What makes it special: Chef-driven French-Mexican plates served in a lush, design-focused space.
#4
Xoco
8.5
Vibes:
Quick Bites Champions
Cheap Eats Budget Brilliance
Solo Dining Sanctuaries
Family Friendly Favorites
Xoco is Rick Bayless’s counter-service spot for tortas, caldos, and churros, pulling steady lines of River North office workers and tourists. The food leans comforting and bold—smoky pork, crispy chicken, deep broths—served fast enough for lunch but satisfying enough for a casual dinner.
Must-Try Dishes:
Baja Chicken Torta, Ahogada Torta, Churro Sundae
What makes it special: High-flavor tortas, soups, and churros from a counter-service Bayless spot.
#5
Mercadito
8.5
Mercadito runs a loud, cocktail-heavy room built around shareable tacos, guacamoles, and ceviches. It’s a staple for pre-club dinners and group outings where guests want modern plates, pitchers of margaritas, and a party-forward River North feel.
Must-Try Dishes:
Tradicional Guacamole, Pastor Tacos, Ceviche de Camaron
What makes it special: High-energy tacos-and-tequila hub with multiple guacamoles and strong drinks.
#6
Bar Sótano
8.4
Hidden beneath Clark Street, Bar Sótano is an agave-focused speakeasy with a serious small-plates kitchen. Mezcal-heavy cocktails meet tlayudas, aguachiles, and bar bites that feel more chef-driven than typical bar food, making it ideal for nights that start with drinks and end as dinner.
Must-Try Dishes:
Black mole tlayuda, Bone marrow esquites, Shrimp and scallop aguachile
What makes it special: Mezcal-centric basement bar where inventive Mexican small plates match the cocktails.
#7
Barrio
8.3
Vibes:
Girls Night Out Approved
Group Dining Gatherings
Happy Hour Hotspots
Birthday & Celebration Central
Barrio is a sprawling, rustic-industrial space for creative tacos, big-format platters, and a deep tequila list. It leans social and loud, functioning as a go-to for birthdays, office outings, and game-day groups that want shareable plates and approachable flavors.
Must-Try Dishes:
Carne Asada, Carnitas Fried Rice, Taco Tower
What makes it special: Large-format Mexican spot with build-your-own tacos and strong tequila service.
#8
Matilda
8.2
Vibes:
Date Night Magic
Trendy Table Hotspots
Instagram Worthy Wonders
Birthday & Celebration Central
Matilda blends Peruvian and Mexican influences in a polished River North dining room, pairing ceviches and grilled seafood with a contemporary tasting-style menu. It’s newer to the neighborhood but already reads as a chef-driven option for diners seeking something more nuanced than standard tacos-and-margs.
Must-Try Dishes:
Lomo Saltado, Pescado Zarandeado, Matilda's Paella
What makes it special: Upscale Peruvian-Mexican cooking with ceviches and composed seafood plates.
Worthy Picks
#9
Mexi-Tacos
7.9
Vibes:
Quick Bites Champions
Cheap Eats Budget Brilliance
Hidden Gems Heaven
Solo Dining Sanctuaries
Mexi-Tacos is a compact taqueria tied to a longtime Chicago food truck, turning out breakfast burritos, classic tacos, and daily specials at wallet-friendly prices. It skews more takeout and quick lunch than night-out destination, but locals lean on it for straightforward, satisfying plates.
Must-Try Dishes:
Chicken Tacos, Breakfast Burrito, Tamales
What makes it special: Brick-and-mortar offshoot of a local Mexican truck with honest, affordable plates.
7.7
Moe’s Cantina River North is a sprawling bar-restaurant geared toward game days, Taco Thursdays, and big-group nights out. Expect solid tacos, fajitas, and shared appetizers rather than chef-y experimentation, backed by loud music, TVs, and plenty of tequila.
Must-Try Dishes:
Fajitas Con Arrachera, Carne Asada Tacos, Elotes
What makes it special: High-capacity cantina mixing tacos, fajitas, and tequila with sports-bar energy.
#11
Zombie Taco
7.6
Operating out of the Moxy Chicago Downtown, Zombie Taco is a nearly all-day, late-night counter for tacos, burritos, and breakfast items. It’s more about convenience and fun flavors than purist tacos, but long hours make it a reliable option after bars or before early flights.
Must-Try Dishes:
Jalapeño Bacon Taco, Braised Brisket Taco, Zombie Burrito
What makes it special: Hotel-side taco counter slinging breakfast and late-night tacos every day.