Best Pizza Restaurants in Midtown East (10022)
6 hand-picked restaurants, critic-reviewed and ranked
Last Updated: January 2026
Our Top Pick
My Pie Pizzeria Romana
High-volume Roman-style pizza with crackly, airy slabs and serious topping work.
Notable Picks
8.6
Roman-style al taglio slabs, long-fermented dough, and imported toppings make My Pie the most distinctive slice in this part of Midtown East. Lines move quickly at the narrow counter, and regulars come for crisp, airy squares that eat more like artisanal focaccia than standard New York slices.
Must-Try Dishes:
Truffle Oil and Mushroom slice, Grandma Nonnina square, Buffalo mozzarella Margherita
What makes it special: High-volume Roman-style pizza with crackly, airy slabs and serious topping work.
8.5
This tiny Sutton Place shop is known for meticulous classic slices and the ticketed DoughDici pan pizza, which has drawn national press. Seating is limited, but the attention to dough, sauce, and toppings makes it a destination-level stop for serious pizza fans.
Must-Try Dishes:
DoughDici pan pizza, Spinach dip slice, Classic grandma slice
What makes it special: Cult-favorite DoughDici pan pie and elevated classic slices in a tiny shop.
8.2
Brooklyn Pizza Masters brings a Brooklyn-style, chef-driven approach to hefty New York slices and squares on 1st Avenue. The menu leans into grandma and Sicilian pies with thoughtful toppings, making it a reliable choice for both a quick slice and a shareable whole pie.
Must-Try Dishes:
Grandma pizza with pepperoni, Upside Down Sicilian, Blackberry & ricotta pizza
What makes it special: Brooklyn-influenced grandmas and Sicilians with creative toppings in a casual room.
Worthy Picks
7.9
Vibes:
Cheap Eats Budget Brilliance
Late Night Legends
Quick Bites Champions
Solo Dining Sanctuaries
LaVista is a high-volume neighborhood slice shop known for generous portions, late hours, and a surprisingly broad menu that includes vegan and gluten-free options. It’s more functional than pretty, but locals lean on it for quick, affordable slices and big heroes.
Must-Try Dishes:
Vodka slice, Bruschetta hero, Vegan margherita slice
What makes it special: Dependable, budget-friendly slices with strong delivery and late-night hours.
Vibes:
Comfort Food Classics
Family Friendly Favorites
Group Dining Gatherings
Quick Bites Champions
Two doors from Sofia, Marinara offers a larger dining room and a menu built around big, saucy Sicilian pies. The MVP slice, striped with marinara, vodka, and pesto sauces, has become a photogenic calling card alongside solid classic rounds.
Must-Try Dishes:
MVP square slice (marinara, vodka, pesto), Vodka Sicilian slice, Buffalo chicken slice
What makes it special: Roomy slice shop with saucy Sicilian pies, especially the tri-sauce MVP.
7.6
La Pizza Italia is a newer, compact counter spot that leans on late-night hours, value deals, and customizable slices. It’s more of a practical neighborhood workhorse than a destination, but the burrata-topped slices and pasta promos make it a useful option in the area.
Must-Try Dishes:
Burrata basil slice, Vodka pasta BOGO special, Pepperoni slice
What makes it special: Late hours and frequent deals on slices and pasta near 2nd Avenue.