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Best Pizza Restaurants in Uptown & Andersonville (60640)

8 hand-picked restaurants, critic-reviewed and ranked

Last Updated: January 2026

Our Top Pick
Spacca Napoli Pizzeria
Neapolitan technique that stays consistent at very high volume.

Notable Picks

$$ Ravenswood
A Neapolitan-focused pizzeria where the crust is the headline—soft center, blistered edge, and toppings that stay disciplined. Locals come for classic pies and a steady rotation of Italian imports, and it’s one of the most reliable “pizza night, no regrets” rooms in this part of town.
Must-Try Dishes: Margherita pizza, Prosciutto e rucola pizza, Tiramisu
What makes it special: Neapolitan technique that stays consistent at very high volume.
$$ Andersonville
A long-running Andersonville institution that’s best when you treat it like a classic Chicago Italian night: big portions, familiar recipes, and an easy-going dining room. The strength is consistency at scale—great for groups, celebrations, and repeat takeout orders that need to hit the same every time.
Must-Try Dishes: Chicken Vesuvio, Lobster ravioli, Calamari fritti
What makes it special: A true neighborhood Italian anchor with proven, high-volume reliability.
8.4
$$ Uptown
A laid-back room with serious execution—Roman-leaning pizzas plus house-made pastas that keep it from being a one-trick pizzeria. It’s strongest when you split one oblong pizza and add one pasta, letting the kitchen show range without over-ordering.
Must-Try Dishes: Diavola-style pizza, Mezze maniche alla carbonara, Squid ink spaghetti with clams
What makes it special: Bib Gourmand-caliber pizza and pasta in an unfussy neighborhood room.
$$$ Andersonville
A Detroit-style specialist where the appeal is caramelized edge, sturdy squares, and topping combos that eat like a full meal. It’s best as a takeout-first play—commit to one pan, add one side, and let the crispy corners do the work.
Must-Try Dishes: Detroit-style pepperoni pizza, The Goods (signature loaded Detroit-style pie), Chubbies (pepperoni rolls)
What makes it special: Detroit-style pans with a real caramelized edge and heavy satisfaction.

Worthy Picks

$$ Andersonville
A bar-forward pizza room built for hang time: pitchers, cocktails, and shareable pies that fit a casual, late-ish schedule. Treat it like a social meal—one tavern-style pie for the table, a second only if the room’s still hungry.
Must-Try Dishes: Tavern-style pepperoni (square cut), Sausage + giardiniera pizza, Cheese pie with chile-honey-style finish
What makes it special: Bar energy first, with shareable pies that match the hangout vibe.
$$ Edgewater
A neighborhood pizzeria with an expansive menu that leans into specialty pies and crowd-pleasing classics. It shines as a practical, reliable option for groups and takeout—order one signature pizza, add one hearty pasta, and you’re set.
Must-Try Dishes: Chicago Classic pizza, Aroma Special pizza, Honey Buffalo Chicken pizza
What makes it special: A deep specialty-pizza bench with a longstanding neighborhood footprint.
$ Uptown
A classic neighborhood pizza shop that leans into fast service, big slices, and familiar Chicago-area comfort. It shines when you order simply—thin crust or a slice-and-salad combo—so the value stays the headline.
Must-Try Dishes: Thin-crust sausage pizza, Pepperoni slice, Stuffed pizza
What makes it special: Big-slice, fast-service pizza that’s built for everyday cravings.
$$ Uptown
A straightforward neighborhood counter built around no-fuss pies and takeout convenience. The best path here is one focused pizza—especially a sauce-and-topping combo you already know you like—because the strength is simple satisfaction, not maximal customization.
Must-Try Dishes: Buffalo chicken pizza, Pepperoni pizza, Cheese pizza
What makes it special: No-frills counter pizza that’s built to solve a quick craving.