Best Mexican Restaurants in Near South Side
2 hand-picked restaurants, critic-reviewed and ranked
Last Updated: February 2026
Our Top Pick
Casa Tulum
Design-forward Mexican seafood spot where quesabirrias, ceviches, and cocktails are served in a Tulum-inspired room.
Notable Picks
#1
Casa Tulum
8.4
Casa Tulum brings a Tulum-inspired, seafood-leaning Mexican menu to the South Loop with beachy decor, cocktails, and a more polished dining-room feel. It’s used for date nights and small groups looking for quesabirrias, ceviches, and composed plates rather than basic combo platters.
Must-Try Dishes:
Quesabirrias, Torta Ahogada, Shrimp Ceviche
What makes it special: Design-forward Mexican seafood spot where quesabirrias, ceviches, and cocktails are served in a Tulum-inspired room.
8.2
La Cantina Grill is a South Loop Mexican staple near McCormick Place, combining a full bar, broad menu, and a sizable vegan offering. It’s where locals, convention-goers, and families converge for fajitas, enchiladas, and margaritas before events or casual dinners.
Must-Try Dishes:
Traditional Enchiladas, Shrimp Fajitas, Mayan Tamales
What makes it special: High-volume South Loop cantina with a full bar, broad vegan-friendly menu, and flexible seating near Soldier Field and McCormick Place.