Best Girls Night Out Approved Mexican Restaurants in River North

Mercadito runs a loud, cocktail-heavy room built around shareable tacos, guacamoles, and ceviches. It’s a staple for pre-club dinners and group outings where guests want modern plates, pitchers of margaritas, and a party-forward River North feel.

Hidden beneath Clark Street, Bar Sótano is an agave-focused speakeasy with a serious small-plates kitchen. Mezcal-heavy cocktails meet tlayudas, aguachiles, and bar bites that feel more chef-driven than typical bar food, making it ideal for nights that start with drinks and end as dinner.

Barrio is a sprawling, rustic-industrial space for creative tacos, big-format platters, and a deep tequila list. It leans social and loud, functioning as a go-to for birthdays, office outings, and game-day groups that want shareable plates and approachable flavors.

CocoBar is a bright pink Riverwalk-side spot pairing frozen margaritas and carnitas tacos with skyline views. It’s more about patio energy and drinks than precision cooking, but the tacos, churro fries, and aguas frescas make it one of downtown’s more compelling Mexican-leaning riverfront options.

Ghost Donkey is a mezcal-and-tequila lounge modeled after Mexican speakeasies, known for neon-pink lighting, party energy and a happy hour built around margaritas and nachos. With a focused snack menu and strong cocktail program, it’s more of a drinks-first stop than a full dinner but functions as a high-energy happy hour destination.

The Miami-born Bodega brand’s River North location pairs a casual front taqueria with a tequila-heavy bar and late-night energy. Tacos de birria, al pastor, and quesabirria headline a menu built for pregame bites, cocktails, and DJ-fueled nights in a space that leans more party than quiet sit-down.

Moe’s Cantina River North is a sprawling bar-restaurant geared toward game days, Taco Thursdays, and big-group nights out. Expect solid tacos, fajitas, and shared appetizers rather than chef-y experimentation, backed by loud music, TVs, and plenty of tequila.