Best Pizza Restaurants in River North

Since 2005, Quartino has operated as River North’s all-purpose Italian enoteca, turning out housemade pastas, Neapolitan-style pizzas, and antipasti in a loud, always-busy room. Enormous multi-platform review volume and steady crowds at nearly all hours make it a default choice for groups wanting shareable Italian without formality.

Siena Tavern leans into a loud, party-friendly take on modern Italian, pairing housemade pastas and pizzas with big-format cocktails and a DJ-adjacent vibe. Since 2013 it has anchored Kinzie’s going-out strip for groups who want sharable plates and a social scene in one stop.

Perched along the riverwalk, Pizzeria Portofino focuses on hand-stretched pizzas, coastal-leaning salads, and spritzes with a strong patio-first mentality. The combination of waterfront views, shareable pies, and approachable pricing makes it a go-to for casual Italian lunches and group dinners in warm weather.

Since 2014, Dough Bros has been the go-to New York–style slice window in 60654, staying open as late as 4 a.m. on weekends. Counter service, foldable slices, and subs make it the quintessential post-bar pizza stop near the State & Hubbard cluster of nightlife.

This family-run gem between the Wrigley Building and Trump Tower serves authentic Italian thin-crust pizzas with traditional toppings in a relaxed, no-frills atmosphere. Italian-born chef takes pride in scratch-made preparations since 2011.

Parlor Pizza Bar’s River North outpost is a huge, sports-friendly pizza hall with wood-fired pies, a long beer list, and an almost-club energy on busy nights. Locals use it for casual group meet-ups, watching games, and sharing pizzas like the Bee Sting and Sgt. Pepper alongside big salads and bar snacks.

The birthplace of deep dish pizza stands as a registered Chicago landmark where Ike Sewell's 1943 creation launched a culinary revolution. Fresh dough made daily, original recipe maintained for over 80 years in the historic original building.

Opened in 2025 by Boka Restaurant Group, Zarella does both tavern-style squares and artisan round pies alongside starters and a few Italian American plates. Its grab-and-go window and relatively moderate pricing make it a newer, more casual entry into the River North Italian landscape.

Authentic Neapolitan-style pizza crafted by Rossopomodoro-trained pizzaioli inside the 64,000 square foot Italian marketplace. Wood-fired 900°F ovens produce charred, elastic crusts with San Marzano tomatoes and creamy mozzarella.

Pizzeria Ora is a long-running downtown spot attached to the Best Western River North, specializing in classic Chicago deep dish plus thin-crust tavern pies in a straightforward, family-friendly dining room. It’s a quieter, more local-feeling option for visitors who want traditional deep dish without queuing at the big-name chains.