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Best Mexican Restaurants in Little Italy

6 hand-picked restaurants, critic-reviewed and ranked

Last Updated: February 2026

Our Top Pick
Santo Taco
Chef-driven taqueria spotlighting steak trompo and polished CDMX-style tacos.

Notable Picks

$$ Little Italy Mexican, Tacos
From a Cosme cofounder, Santo Taco brings CDMX-inspired tacos like the much-praised steak trompo to a compact Nolita counter next to La Esquina. Portions are slightly larger than street tacos, with careful toppings and a modern look that has quickly made it a downtown taco benchmark.
Must-Try Dishes: Santi’s steak trompo taco, Pork carnitas taco, Zucchini and poblano taco
What makes it special: Chef-driven taqueria spotlighting steak trompo and polished CDMX-style tacos.
$$ Little Italy Vietnamese, Pho
5ive Spice’s Nolita outpost blends slow-simmered pho, banh mi, and shaking beef with its signature bánh xèo tacos in a compact, buzzy setting. High multi-platform ratings and steady crowds point to reliable execution, especially for the broths and short rib dishes, even if prices run higher than a traditional hole-in-the-wall.
Must-Try Dishes: Braised Short Rib Bánh Xèo Tacos, Classic Pho Noodle Soup, Short Rib Banh Mi
What makes it special: Modern Nolita Vietnamese with standout bánh xèo tacos and richly built pho.
$ Little Italy Mexican, Tacos
A late-night taco counter built for post-midnight cravings: fast pacing, bold salsas, and a menu that stays focused on tortillas-first satisfaction. Best when you want quick, hot tacos without the full sit-down ceremony.
Must-Try Dishes: Quesabirria tacos, Carne asada taco, Baja taco
What makes it special: A true late-night taco option that stays open very late.
$$$ Little Italy Mexican, Tacos
For nearly two decades this Nolita/SoHo border institution has combined a streetside taqueria, corner café, and subterranean brasserie into one of downtown’s best-known Mexican addresses. Guests come for queso fundido, fish tacos, and late-night energy more than quiet refinement.
Must-Try Dishes: Pescado tacos (char-grilled market fish), Queso fundido with queso Chihuahua and chile de árbol, Bistec con queso rib-eye tacos
What makes it special: Multi-level Mexican spot pairing a grab-and-go taqueria with a hidden brasserie and tequila bar.

Worthy Picks

$ Little Italy Mexican, Tacos
A compact taqueria move for when you want fast, filling Mexican street-food staples in the neighborhood without committing to a full-service night. It’s strongest as a grab-and-go taco and burrito stop, especially when you lean into the house specials rather than over-customizing.
Must-Try Dishes: Burrito, Tacos, Gallo fries
What makes it special: A fast taqueria option for burritos and tacos off Broome.
7.6
$$$ Little Italy Mexican, Tacos
A SoHo Mexican dining room with a more date-friendly, sit-down feel and a menu that leans into classic preparations rather than street-food minimalism. It’s a good pick when you want a longer meal with cocktails and shared plates, but the value proposition depends on ordering smart.
Must-Try Dishes: Cochinita pibil, Guacamole, Happy hour oysters
What makes it special: A SoHo sit-down Mexican room built for cocktails and shared plates.