Best American Restaurants in SoHo
2 hand-picked restaurants, critic-reviewed and ranked
Last Updated: February 2026
Our Top Pick
Manuela
Gallery-like space where seasonal American plates and contemporary art share the stage.
Notable Picks
#1
Manuela
8.3
Set inside an airy SoHo art space, Manuela serves seasonal American cooking with a gallery’s sense of composition, from roasted vegetables to polished desserts. Opened in 2024, it’s quickly earned strong notices for refined, produce-driven plates and a room where contemporary artworks share the spotlight with the open kitchen.
Must-Try Dishes:
Roasted Cauliflower with Date Vinegar & Almond, Salt-Roasted Sunchokes with Ricotta & Celery, Pavlova with Seasonal Market Fruits
What makes it special: Gallery-like space where seasonal American plates and contemporary art share the stage.
#2
Fanelli Cafe
8
Vibes:
Cheap Eats Budget Brilliance
Comfort Food Classics
Late Night Legends
Solo Dining Sanctuaries
Operating on this corner since the 19th century, Fanelli Cafe is one of New York’s oldest bar-restaurants, now serving straightforward pubby American fare to artists, locals, and visitors in a time-worn room. Burgers, chili, and open-faced tuna melts anchor a menu that’s more about atmosphere, value, and history than trend-chasing.
Must-Try Dishes:
Fanelli's Burger with Fries, Open-Faced Tuna Melt with Cheddar, Moroccan Lamb Stew
What makes it special: Historic SoHo tavern where burgers, chili, and martinis meet creaky floors and decades of stories.