Best Pizza Restaurants in Upper East Side-Lenox Hill-Roosevelt Island
2 hand-picked restaurants, critic-reviewed and ranked
Last Updated: February 2026
Our Top Pick
Patsy’s Pizzeria
Coal-oven style pies from a long-running New York pizzeria group in a comfortable sit-down space.
Notable Picks
8.6
Patsy’s Pizzeria on 60th brings the brand’s historic coal-oven style to Lenox Hill, serving thin-crust pies and classic Italian starters in a full-service setting. It isn’t a 3am slice joint, but for later dinners and lingering pizza-focused nights, it’s one of the most established options in 10022.
Must-Try Dishes:
Old Fashioned Margherita Pizza, White Pie, Baked Clams
What Makes it Special: Coal-oven style pies from a long-running New York pizzeria group in a comfortable sit-down space.
Worthy Picks
7.9
Uncle Vinny’s is a newer mom-and-pop shop on First Avenue that has quickly become a go-to for grandma slices, late-night pies, and a broader menu of pastas and wings. With hours that regularly run past midnight and later on weekends, it fills the gap between old-line slice joints and newer comfort-focused spots.
Must-Try Dishes:
Grandma Pizza Slice, Grandma Pesto Pizza, Thin-Crust Neapolitan Pie
What Makes it Special: Mom-and-pop late-night shop built around strong grandma slices.