Best Happy Hour Hotspots Mexican Restaurants in Mission
3 hand-picked restaurants, critic-reviewed and ranked
Last Updated: February 2026
Our Top Pick
Loló
Vivid design and Jaliscan-inspired plates with agave-centric cocktails.
Notable Picks
#1
Loló
8.5
Jaliscan-Californian plates and a serious agave list in a colorful, design-forward room; weeknight drink specials make pre-dinner cocktails popular. Fried avocado tacos and seafood tostadas anchor the menu.
Must-Try Dishes:
Fried avocado taco, Tuna tostada, Carnitas en cazuela
What Makes it Special: Vivid design and Jaliscan-inspired plates with agave-centric cocktails.
8.4
Neighborhood standby for agave cocktails and mix-and-match tacos with a weekday happy hour that draws after-work crowds. Portions are fair, salsas are bright, and the room hums without getting chaotic.
Must-Try Dishes:
Guajillo-braised beef taco, Chicken tinga taco, Queso dip with chips
What Makes it Special: Reliable weekday happy hour with a deep agave program.
#3
Mosto
8.1
Mezcal-focused Mexican cocktail bar with a concise menu of tacos and bar bites plus a value-driven early evening happy hour. Counter seating and standing room keep it casual and fast.
Must-Try Dishes:
Al pastor taco, Quesabirria, Chips with guacamole
What Makes it Special: Weekday HH mezcal and margarita deals with tacos to match.